Open Source Drug Discovery

OSDD is a CSIR led team India consortium with global partnerships to provide a platform where the best minds can collaborate and collectively endeavor to solve the complex problems associated with discovering novel therapies for neglected tropical diseases like Malaria, Tuberculosis, Leshmaniasis, and so on. This project has provided unique opportunity for scientists, doctors, technocrats, students and others with diverse expertise to work for a common cause. Launched in september 2008, with tuberculosis as its first disease target, the OSDD consortium already has more than 6900 registered users from more than 130 countries around the world, and has emerged as the largest collaborative effort in drug discovery. Besides, the involvement of laboratories and biotech firms, OSDD works closely with students and faculty of the universities and leading institutes in India and abroad. The OSDD units in universities provide intellectual resource and student taskforce.

Wellness Genomics Project

Human body is an intricate biological machine, capable of interacting and dynamically adapting to the environment around it. The longevity of this machine is intricately related to nature and nurture and how the static genetic code allows and accommodates dynamic interactions and adaptations. Recent studies suggests that clues towards understanding this framework could be derived from a genomics approach. The advances in technology in the area of nucleotide sequencing has contributed tremendously to the scale of genome sequencing with associated drastic reduction in costs, which now opens up the possibility of finding answers to biological question on a unbiased genome-scale approach. We hypothesise that apparently healthy individuals with higher lifespans could potentially encode for an optimal genome, characterized potentially by fewer number of variations which could predispose the individuals to diseases or genomic variations which could confer protective phenotypic outcomes.